Since different GSH-degrading enzymes are oriented to either intracellular or extracellular GSH pools, intracellular degrading enzymes directly decrease intracellular levels of GSH

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Environmental Exposures Air pollution, cigarette smoke, heavy metals, and various environmental toxins can all increase free radical production
The GSH-GSSG ratio is an important indicator of the efficiency of our metabolism and the amount of cellular oxidative stress
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