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2.1 Pharmacokinetics & Safety IV MOTS-c (5 mg kg) displayed a 41-min terminal half-life and no change in ALT/AST or corticosterone.[1] No adverse hematological findings after 28-day repeat-dose murine study (10 experimental dose).[13] 2.2 Metabolic & Weight-Loss Data Diet-induced-obese mice lost 14 % body weight over 4 weeks vs

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4.1 Standardization and quality control issues Natural metabolites derived from botanical drugs can have significant variability in content and potency

doi:10.1155/2016/3593951

Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines

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