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Description

Poly IC triggers a cathepsin D- and IPS-1-dependent pathway to enhance cytokine production and mediate dendritic cell necroptosis

Mechanistically, SIRT1 negatively regulates p16 and p21, essential in driving senescence in response to DNA damage

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Used together, the two pulses combine for a much bigger release than either could produce alone

Gallic acid is found in various fruits and plant products (such as berries, tea, nuts, and red wine) either in free form or as part of tannins and other polyphenols (32)