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Recent understandings of biology, prophylaxis and treatment strategies for hypertrophic scars and keloids

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Contexto histrico e cientfico O interesse cientfico pelos peptides dos fatores de crescimento peptides consideravelmente no final do sculo XX, medida que os investigadores procuravam compreender melhor as vias de sinalizao molecular envolvidas na comunicao celular

using single-cell transcriptomic profiling, identified distinct CAF subpopulations, including inflammatory CAFs (iCAFs) and myofibroblastic CAFs (myCAFs), each with unique gene expression signatures and functional roles

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