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Ratjen et al

Transforming growth factor beta (TGF-) is a major cytokine that promotes ECM accumulation

IV therapy costs $199-$400+ per session with typical protocols requiring 1-3 weekly visits, totaling $800-$4800+ monthly

Our results demonstrated that the developed LUT-EX@MN led to a significant decrease in TIMP1 levels by only 1.28-fold change compared to the negative control group, thereby contributing to its IOP-lowering effect (Fig