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10.3389/fphar.2022.873090 246 TangZ.HuoM.JuY.DaiX.NiN.LiuY.et al (2021b)

2.2 Immune cytokines responses after an ischemic stroke Immune cytokines secreted by immune cells are promising prognostic and predictive biomarkers for predicting stroke outcomes and therapeutic targets in patients with IS ( 2.2.1 Proinflammatory cytokines The proinflammatory cytokines mediate brain tissue destruction after an IS

In turn, transcriptional programs regulating complex I biogenesis, FAO, TCA and the ETC along with redox protective programs were highly upregulated as compensatory mechanisms