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Price: 29.45 USD
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Mutations in both HELLS and CDCA7 have been found to disrupt normal DNA methylation patterns, which cause the progression of ICF syndrome (87)

Sci Adv , 6: eaax8358, 2020

Fincham JR, Kinsey JA, Fuentes AM, Cummings NJ, Connerton IF

J Biol Chem 280:1221212220

VavrovaLKodydkovaJZemanMDusejovskaMMacasekJStankovaBet alAltered activities of antioxidant enzymes in patients with metabolic syndrome

To explore gene expression changes, a multivariate reanalysis of the GSE1073233 dataset was performed, revealing major differences between untreated HepG2 and HepG2 ATP7B-KO cells, particularly in autophagy, lipid metabolism, and stress-related pathways