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Conclusion The findings of this study suggest that bromadiolone, when combined with ciprofloxacin, vitamin D, cinnamon, or aspirin, may contribute to enhanced apoptotic responses in liver tissue, as indicated by modulation of p53, p21, cleaved caspase-3, lipid peroxidation, DNA damage, and prothrombin time

doi: 10.1126/science.1087573

I think we still need further explanation

M.ZhangF.GuoZ.DaiQ.PajdzikK.LiY.et al

Studies have suggested that IGF-1 and myostatin/Smad pathways cross-talk at different levels

Among them, SecB-dependent and SRP-mediated pathways both complete the translocation process by binding to SecA, and genetic fusion of signal peptides to RPs can enable them to utilize these pathways to translocate