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2) and (2) the seven reported suppressor mutations from the yeast model of disease can be all mapped onto the hydrophobic face of the regulatory domain that forms the BatemanBateman interface (Fig

doi: 10.1016/j.exger.2020.111118 75

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Ritonavir is nowadays used primarily to increase the bioavailability of other HIV drugs as it inhibits their major metabolising enzyme, P450 3A4 monooxygenase [48, 49]