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Science 329 , 407 (2010)

MOR and DOR activation in the DLS and DMS produce antagonist-irreversible LTD in young rats and mice as well as adult mice (Fritz et al., 2018

doi:10.2174/1381612827666210707093202

For danuglipron, most AE were mild in severity at the phase 2 trial for people with T2D, but 2234% of participants receiving the higher doses (80 mg twice daily) discontinued the medication due to AE (vs