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However, there is paradox about the effect of AMPK on AD

This event might occur as a result of the rearrangement and fusion of several chromosomal segments (Xu et al., 2012)

We investigated whether this regulation was dependent on modulation of DGAT2 and GPAT4 targeting the LD surface

Further, this complex binds with hypoxia-responsive elements (HREs) and activates the gene expression for the NOX genes ( NOX1, NOX 2, NOX 4 , and NOX 5 ) NOX enzymes also contribute to the production of free radicals Superoxide and hydrogen peroxide (50) by transferring the electrons from NADPH to oxygen (51)

Average surface temperatures have risen by 0.2 C per decade since 1970, faster than in any other 50-year period, with projections of a further 1.4 C to 4.4 C increase by 2100 (IPCC, 2023)