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In elderly subjects, Epithalon administration has been associated with increased nighttime melatonin levels and more normalized circadian melatonin rhythms

Br Dent J 2015

It exists in a space of research and cosmetic application

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But as we mentioned earlier in this guide, acetyl hexapeptide-8 has a mechanism of action similar to Botox (though its not as strong of an effect),22 and it has demonstrated the ability to reduce the appearance of wrinkles.23 However, more research is needed, as some other research has found the peptides effects to be unremarkable.24 The other peptide in the complex is pentapeptide-18, also known as Leuphasyl