genes involved in glutathione metabolism Expression of related to and NADPH GLUTATHIONE SYNTHESIS - PMC

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26 Molecular Weight and Lipophilicity The absorption of drugs by the nasal epithelium is influenced by their molecular weight and lipophilicity

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Ozaka S, Sonoda A, Ariki S, Minata M, Kamiyama N, Hidano S, Sachi N, Ito K, Kudo Y, Dewayani A, Chalalai T, Ozaki T, Soga Y, Fukuda C, Mizukami K, Ishizawa S, Nishiyama M, Fujitsuka N, Mogami S, Kubota K, Murakami K, Kobayashi T

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The resulting GSH or homoglutathione (-L-glutamyl-L-cysteinyl--alanine) conjugates were usually much less toxic and more water-soluble than the original xenobiotics (Brown and Neighbors, 1) (Bartling et al., 2002