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Moreover, knockdown of endogenous CDH1 , but not CDC20 or other candidate E3 ubiquitin ligases identified by our IP-MS, rescued the PIN1 degradation induced by the PIN1 inhibitor (Fig

However, the underlying mechanisms connecting DNA methylation and activating totipotency-regulating genes have remained largely unknown

Declarations Competing interests All the three authors declare that they do not have any conflict of interest related to the financial or funding matters