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2 3 The proposed mechanisms include promotion of angiogenesis (new blood-vessel formation), effects on the nitric-oxide system, and stimulation of fibroblast outgrowth and cell migration through signaling pathways such as FAK-paxillin

Its ability to improve sleep quality also plays a significant role in optimising recovery and hormonal balance

However, its use in clinical trials for kidney transplantation did not show benefit over standard care and was associated with decreased graft function and increased adverse effects compared to standard treatments [96,97,98]

Vitamin B12 is a key player in energy metabolism, aiding in the conversion of food into energy

This requires more pharmacological and pharmacokinetic data across the animal models to conclude