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TOV-21G and KOC-7C cells were treated with erastin (10 M) for 4 hours and GSH levels were assayed using GSSG/GSH Quantification Kit

These unstable carbon core free radicals rapidly react with oxygen to generate polyunsaturated fatty acids (PUFAs) peroxygen free radicals, consequently triggering cell death

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Furthermore, the dysregulation of Hepcidin and Ferritin expression in ferroptosis has implications for, IE

In Graves disease, selenium supplementation might lead to faster remission of hyperthyroidism and improved quality of life and eye involvement in patients with mild thyroid eye disease

doi: 10.1016/j.jobcr.2025.06.006 35 KumarADavuluriGWelchNKimAGangadhariahMAllawyAet al