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doi: 10.1016/j.yjmcc.2005.02.020

[12] had some methodological points of criticism

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Caspases are synthesized as proenzymes and require proteolytic processing to be catalytically active

Studies in animal models of glaucoma and in isolated cells show that most glaucoma-relevant cell types (trabecular meshwork cells, retinal glia and RGCs) respond to pressure with fast onset electrical and calcium signals (~milliseconds to ~seconds), whereas sustained exposure to mechanical stressors tends to evoke phenotypes that are characteristic of glaucomatous injury

When asked how the fancy patch had treated me by a colleague, I replied, I feel fine, but not as if I didnt drink. I followed up with Pomrenze to ask about our two only real criticisms of the patch: That it seemed to reduce drunkenness for one of us, and wasnt great at staying stuck