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Scutellarein modulates the GPX4 antioxidant system to thwart ferroptosis in chronic obstructive pulmonary disease induced by LPS and cigarette smoke in mice (Liu L

Increased expression of PHGDH and prognostic significance in colorectal cancer

In sweet cherry, 37 pairs of genes were duplicated, along with WGD (three pairs), TRD (four pairs), DSD (11 pairs), TD (10 pairs), and PDs (9 pairs), indicating the gene familys growth (Figure 4 and Supplementary Table 3)

For example, decreased sodium excretion (increasing levels) results in water retention and a condition known as volume overload, which causes swelling of tissues (edema)

In contrast, deletion or inhibition of GPX4 causes rapid H 2 O 2 accumulation and RIPK3-mediated necrosome activation 72,73

Patient stories and the human side Clinical practice is full of examples that illustrate both the promise and the complexity of these tools