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A recent proteome study connected GPX3, ROS generation and kidney fibrosis in CKD 20,21

The Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling pathway further mediates this inflammatory response in chronic glaucoma (149, 150)

[15] and Vedaei et al

However, the dicovery of these interactions with biotic and abiotic factors are recent and require further studies to fully understand their effects on different species