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Pyruvate carboxylase suppression via shRNA slows non-small-cell lung cancer xenograft growth in NSG mice by 2-fold, reduces endpoint tumor weight by 30%, and impairs key metabolic pathways supporting tumor proliferation [2]

PC3 model of prostate cancer For the prostate cancer experiments, 12-week-old NRG male mice were used

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Cell cytoplasm constitutes the most abundant pool of ascorbate, while to some extent it is also transported across plasma membrane (usually 5%) to the apoplast (Barnes et al., 2011

599 Ndfip1 overexpression may restore mitochondrial dysfunction in PD mice by regulating voltage-dependent anion-selective channels

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