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This indicates that as the powerhouse of the cell, the functional integrity of mitochondria is of vital significance for the survival of such neurons

Glutathione levels decreased under iron exposure in both WT and gsh strains, consistent with an oxidative stress response

doi: 10.1074/jbc.ra117.001385

Involvement of glutaredoxin-1 and thioredoxin-1 in beta-amyloid toxicity and Alzheimer's disease

J., Johnson, C

Where indicated, to interfere with N-glycosylation, cells were grown in glucose-depleted medium or treated with 0.1 g/ml of Tunicamycin (Tun) (Sigma-Aldrich, St