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Anti-epileptic drug treatment in children: hyperhomocysteinemia, B-vitamins and the 677C T mutation of the methylenetetrahydrofolate reductase gene

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The DUB CYLD inhibits ubiquitinated degradation of IB, whereas the E3 ligase Trim29 promotes ubiquitinated modification of IB, which affects NF-B activity and influences DKD progression