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Glycine can be interchanged with serine 41 , and glutamate can be converted to glutamine 42

5 Mitochondrial metabolism, inflammatory tone and insulin resistance As mentioned above, LAC is an endogenous compound essential for -oxidation and is an emerging epigenetic modulator of glutamatergic function

The top three research priorities were found to be (1) understanding the biological mechanism behind PEM and how this can be treated or managed (2), which existing drugs used for other conditions would be useful in treating ME/CFS, and (3) finding accurate and reliable diagnostic testing for ME/CFS