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Effects of sex and age on the 24-hour profile of growth hormone secretion in man: importance of endogenous estradiol concentrations

The underlying work describes when the body's own GH pulse tends to be strongest, not when a user should administer anything

Because IGF-1 signalling promotes cell proliferation, a recognized theoretical concern is that it could promote the growth of existing tumors , and excess dosing can cause hypoglycemia

Post-stress studies: Frequently used in frameworks involving mechanical loading and adaptive remodeling

Rediger et al., 2009)

The saturation heuristic is best understood as a plausibility argument for why a figure near 100 mcg is not obviously absurd, not as evidence that it is correct