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Curr Opin Neurobiol 15:282288 Mayer ML (2011) Structure and mechanism of glutamate receptor ion channel assembly, activation and modulation

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Increased LKB1 and AMPK activity results in nuclear to cytoplasmic HuR translocation and the subsequent stabilization of several cyclin mRNAs enhancing cell proliferation[130]

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These modifications often alter the structure and function of the protein