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The global efficacy of these treatments is limited, even when used in combination, as also demonstrated by systematic reviews and meta-analyses ( The recent advances in the understanding of vitiligo pathogenesis have promoted new therapeutic alternatives

two-tailed unpaired t -test

Host-parasite interaction and immunomodulation Parasitic helminths are believed to have coevolved with humans over millennia, continuously refining and improving their mechanisms to skew or suppress the hosts immune response to establish a sustained niche inside their host

[DOI] [PubMed] [Google Scholar] 20.Alizadeh M, Karimi F, Fallah MR

The mechanisms underlying the specific effect on infarct volume remain to be identified, but one possibility is that the protection is mediated through increased astroglial activation in the border zone of the infarct 569