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Description

Especially during the differentiation of esophageal squamous epithelium, BMP-driven ROS production activates Nrf2-mediated oxidative stress response, a mechanism crucial for normal epithelial differentiation [122]

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While early ADAs were related to the murine origin of the first mAb therapeutics, ADAs also occur against fully human mAbs

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PMID: 157

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Thus, LC supplementation could be useful not only to supply the tissues in presence of but also in avoiding oxidative damage as a result of increased amounts of reactive species

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