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Description

Since mitochondrial ROS are upstream activators of NLRP3 inflammasome and NF-kB pathways, reducing them at the source has downstream anti-inflammatory effects throughout the cell

2000;232:41929 PMID: 10973392

Pellegrini A, Hgeli G, von Fellenberg R: Isolation and characterization of two new low-molecular-weight protein proteinase inhibitors from the granule-rich fraction of equine neutrophilic granulocytes