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Unbound iron enters the cardiomyocytes through the L-type calcium channels ( The fact that cardiomyocyte iron overload is a storage problem and not an infiltrative process indicates that iron can be removed to reverse cardiac iron overload and associated damage ( Molecular mechanism of myocardial injury caused by cardiac iron overload in thalassemia Iron overload is a common feature in patients with -thalassemia, but the molecular mechanism of cardiac damage caused by iron overload in thalassemia is poorly understood

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Cardiovascular support: Research suggests TB-500 may support cardiac tissue repair following ischemic events, with studies showing improved outcomes in animal models of heart damage

Appl Surf Sci 383:240247

Neutrophil extracellular traps (NETs) are comprised of modified neutrophilic chromatin that is expelled into the system to neutralize and prevent the dissemination of microbes, whilst concurrently alerting the immune system of the infection [25,26,27]