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Epithalon also seemed to inhibit the activity of Caspase-3, a crucial enzyme believed to facilitate apoptosis (programmed cell death)

Acta Pharmacol Sin 33(3):291 Xue CC, Li H, Yu M, Chong CCY, Fan Q, Tham YC et al (2025) Omega-3 Fatty acids as protective factors for age-related macular degeneration: prospective cohort and mendelian randomization analyses

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Similarly, ovarian oxidative stress model mice exhibit inhibition of the Nrf2/HO-1/GPX4 pathway (Niu et al., 2023), suggesting that GPX4 deficiency-induced ferroptosis may contribute to reduced ovarian reserve

J Clin Endocrinol Metab 89(11):53425348 (2004)

M., and Thatcher, W