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Medications: Certain medications, such as proton pump inhibitors (PPIs) used for acid reflux and metformin for diabetes, can reduce B12 absorption over time

If your protocol requires doses under 3mg, consider reconstituting with a larger solvent volume to increase injection volume and improve accuracy

In addition to folate and vitamin B12 supplementation, you can discuss the potential of other underlying nutritional deficiencies you may have with a doctor to see whether you need to take other supplements