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HDX-MS experiments were performed in two independent experiments, each including three technical replicates per protein and per time point

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Wnt signaling is initiated when Wnt ligands bind to Frizzled (FZD) receptors

D.LundgaardI.SchwichtenbergA

Second, due to the open-label design, both the investigators and participants were aware of the treatment allocation, which could systematically influence the evaluation of therapeutic efficacy