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Our research team conducted a comprehensive search of the Clinical Trials.gov database using keywords including Intervertebral Disc Degeneration and related terms, identifying a total of 576 registered clinical studies

or Have intolerable adverse effects associated with allopurinol treatment requiring treatment discontinuation and have trialled probenecid at doses up to 2 g per day or to a maximum tolerated dose

DG received speaking honoraria from Pfizer and Bristol Meyers Squibb outside the submitted work and participated in this research project funded by Bayer with funds paid to the institution where he is employed

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The risks are real: no required quality control, no contamination testing, incorrect purity or peptide sequence, no physician oversight, and legal exposure for buyers who self-administer