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A.MagdyM.IsmailA.AttiaA.AhmedH.et al

We hypothesized that the addition of cystine would activate the glutathione pathway and alter the GSH/GSSG ratio, thereby disrupting bacterial redox homeostasis

Chapter 16 melatonin and nerve regeneration

Refrigerated storage is necessary to preserve blood until needed for transfusion therapies, but it leads to the progressive accumulation of biochemical and morphological alterations, mainly triggered by oxidative stress to proteins and lipids, a phenomenon known as the storage lesion 9

Accordingly, conditioned medium from Cyb5r3 -KD MLE12 cells had a significantly higher amount of secreted osteopontin at baseline, which went up almost 3-fold further upon stimulation with TGF-1 (Supplemental Figure 12E)