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Studies on IPF lung samples showed increased staining of the ER stress- and UPR activation-associated proteins ER chaperone immunoglobulin heavy-chain-binding protein (BiP), X-box-binding protein 1 (XBP-1), and ER degradation enhancing -mannosidase-like protein (EDEM) in epithelial cells, in comparison with healthy control lung tissues [214]

CKD is also characterized by an increased state of oxidative stress

Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors

10.1016/j.jad.2020.01.102 389 SasakiD.SasakiK.IkutaN.YasudaT.FukudaI.KondoA.et al

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