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Symptom-focused strategies avoid triggers but don't address why cellular processing systems became overwhelmed initially

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The decrease in cellular GSH concentration is an early hallmark in the progression of cell death in response to different apoptotic stimuli in many cell types

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organic acids, ketoacids by BSTFA (N,O-Bis(trimethylsilyl)trifluoroacetamide) and bile acids by methanol +2% sulfuric acid + MSTFA +1% TMCS for NMR ( 4.4 Metabolomic variability among hosts Several studies have used metabolomics to compare the metabolic characteristics of high-growth and/or high-productivity cell lines to identify metabolites that accumulate in the cell or culture and inhibit growth (Figures 4A, D) and/or productivity