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Retention time of each metabolite was determined by authentic standards

Furthermore, metformin significantly induced necrosis in HCT116 cells, when compared to vehicle control ( Figure 3C )

SOCS1-targeted therapy ameliorates renal and vascular oxidative stress in diabetes via STAT1 and PI3K inhibition

Supplementary material The Supplementary Material for this article can be found online at: References 1 AmatullahH.Maron-GutierrezT.ShanY.GuptaS.TsoporisJ