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[95] Intramuscular or intravenous injection [edit] Injection of hydroxycobalamin is often used if digestive absorption is impaired, [2] but this course of action may not be necessary with high-dose oral supplements (such as 0.51.0 mg or more), [97] [98] because with large quantities of the vitamin taken orally, even the 1% to 5% of free crystalline B 12 that is absorbed along the entire intestine by passive diffusion may be sufficient to provide a necessary amount

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92 In another observational study, the prevalence of diabetes was 21% (13 out of 62) in subjects with fibromyalgia compared with less than 8% (315 out of 4,093) in a general population

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Considering GLP-1 receptor agonists as a preferred treatment for diabetes is recommended owing to its cardiovascular protective effects, especially in cases where neuropathy is present, in addition to optimizing glucose control