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These include the severity of deficiency, medical conditions, age, and weight

Then, they get regular doses to keep levels right

The researchers adjusted dosages in subsequent experiments and found they could modulate the kidney impact

To examine if an intact endogenous Trp biosynthetic pathway is sufficient to block V-ATPase-dependent autophagy, we constructed the VMA2-AID*-9MYC strain in a Trp prototrophic background