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Subsequently, we further confirmed that endo-IWR1 suppressed the NTAPP-induced nuclear -catenin in hDP cells (Supplementary Figure 4c)

It is thought that KDs exert their positive effect (among others) via stimulation of mitochondrial biogenesis, improvement of mitochondrial function and decrease of oxidative stress [13,14,15,16] and therefore have been implemented in some cases with MD and epilepsy [12, 17]

ISO 17034 describes competence and consistent operation requirements for reference material producers, reinforcing the broader point that documented identity, value assignment, and traceability matter in analytical-material workflows [15]