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2010) and found 12 miRNAs responsive to APAP overdose enriched in different tissues

Mao C, Liu X, Zhang Y, Lei G, Yan Y, Lee H, Koppula P, Wu S, Zhuang L, Fang B, Poyurovsky MV, Olszewski K, Gan B (2021) DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer

After transiting into the cecum and colon, the host-produced bile acids, known as primary bile acids, are transformed by the gut microbiota into numerous derivatives, known as secondary bile acids

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On the other hand, the increased mutation burden from radiation or chemotherapy can potentially lead to the emergence of new mutations that confer resistance to the therapy (81)