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Salinas et al 27 The traditional treatment of vitamin B 12 deficiency is the intramuscular injection of cyanocobalamin, generally, 1 mg/d for 1 week, followed by 1 mg/wk for 1 month, and then 1 mg every 1 or2 months ad perpetuum

Clinical focus should shift from broad interventions to targeted combinations, such as utilizing phage therapy to clear specific pathogens alongside supplementation with engineered beneficial metabolite-producing strains