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Trkan, F., Huyut, Z., Demir, Y., Erta, F., & Beydemir,

doi: 10.1016/j.jcjo.2018.02.024

Clinical response assessed by global photography and investigator assessment

4.3 The HPA axis Immune-inflammatory mechanisms are closely intertwined with the neuroendocrine system, in which the HPA axis is the core regulatory system for the bodys response to stress, and its dysfunction is one of the most important biological markers of depression