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Supplementary information Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made

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van Beusekom 1 1 Erasmus MC University Medical Center, Department of Cardiology, Rotterdam, Netherlands, 2 Erasmus MC University Medical Center, Stroke Center, Department of Neurosurgery, Rotterdam, Netherlands, 3 Erasmus MC University Medical Center, Stroke Center, Department of Neurology, Rotterdam, Netherlands Background and Aims: Despite successful recanalization, over half of acute ischemic stroke (AIS) patients with large vessel occlusions experience poor outcome

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The first step is a thorough evaluation, which includes a medical history, physical examination, and diagnostic testing, if necessary