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In recent years, nanomaterials enhanced by artificial biofilms and cell membranes have rapidly emerged as a focal point for research in medicine, owing to their enhanced biocompatibility, extended in vivo circulation period, low toxicity, and minimal side effects

Clinical studies have demonstrated that BH 4 supplementation given to diabetic subjects improves their endothelium-dependent vasodilation, indicating that uncoupled eNOS plays a role in diabetic endothelial dysfunction [17-19]

This is because the usual criteria for higher reactivity are not met since each of these electrons has the same spin

doi: 10.1097/MAT.0000000000001985 15 BonilhaCSVerasFPde Queiroz CunhaF

Rolling on E- or P-selectin induces the extended but not high-affinity conformation of LFA1 in neutrophils