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The BNF advises that patients presenting with neurological symptoms should receive 1000 mcg i.m

So the question isn't always whether B12 treatment caused an iron issue - it may be whether one was already there, just less obvious

In the landmark STEP 1 clinical trial, participants using semaglutide 2.4mg achieved an average body weight reduction of approximately 15% at 68 weeks compared to 2.4% in the lifestyle-only group

TARGETS OF PHARMACOTHERAPY IN THE MANAGEMENT OF OBESITY Novel insights provided by pathophysiology indicate the presence of a complex homeostatic system in which information about the energy reserve status and the meal quality and content is relayed from the periphery (gastrointestinal tract, pancreas, and adipose tissue) via specific orexigenic and anorexigenic peptides and hormones to the central nervous system (CNS)

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DOI: [10.1210/endo.142.12.8538] 4