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Houston A stranded motorist escapes floodwaters on Interstate 225 after Hurricane Harvey inundated the Texas Gulf Coast with rain causing mass flooding, in Houston, Texas, August 27, 2017

doi: 10.1200/JCO.2021.39.3_suppl.437 140 TaddeiMLPardellaEPranziniERaugeiGPaoliP

& Erkelens, D

Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+

Evidence from type 1 diabetes also points to an increase in GSH utilization, which in itself was associated with poorer glucose control.The perfect storm of obesity, oxidative stress, inflammation, adipocyte dysfunction, and the related metabolic abnormalities may also be linked by glutathione depletion

In conclusion, we have demonstrated in the present study that exposure of breast epithelial cells in vitro to fatty acids results in epigenetic effects that produce dynamic and profound changes in the expression of genes that have been associated with the development of ER- breast cancer (Fig