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We detected a clear increase in circulating formate levels in 40-week-old KC mice, compared with 25-week-old counterparts that retained higher levels of pancreatic Aldh1l2 expression (Fig

ERO1A is a FAD-dependent enzyme catalyzing the oxidative folding (formation of disulfide bonds) of secretary proteins in the ER 42,43

10.1016/j.addr.2009.09.006 182 MaherS.GeogheganC.BraydenD

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For instance, hematopoietic stem cells (HSCs) have the ability to self-renew and differentiate into different blood cell types

It also regulates EC function, survival, proliferation, and senescence through the SIRT1 and LKB1/AMPK pathways (95)