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Pathway enrichment analysis revealed 15 dysregulated pathways in male PD- GBA1 patients compared to healthy controls, with glycine-serine metabolism being the most significantly affected pathway (involving 11 metabolites)

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However, when agonists were co-applied with EAR-20 in cultured hippocampal neurons, the observed potentiation was lower compared to that seen in GluN1-GluN2A and GluN1-GluN2B di-heteromeric receptors

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Wade Lightheart: Well, that might help tell our bodies, right