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Description

doi: 10.3389/fimmu.2023.1004795 56 CarlsonAKAminMCohenJA

Natural Occurrence in Biology and Environment Thiols are naturally present in various biological and environmental systems

Winter JP, Gong Y, Grant PJ, Wild CP

secondary IR cross-reactivity Key downstream pathways / PI3K-Akt-mTOR and RAS-MAPK-ERK IGF-1 DES comparison / DES is 6-aa truncated, 10x higher potency but even shorter half-life (~20-30 min) Regulatory status / Not FDA-approved for any indication